One of the most prestigious names in luxury spa experiences in the U.S. is Canyon Ranch, and this property - at 70,000-square-feet - is the largest in Florida. The Aquavana thermal spa section includes a Finnish sauna, crystal steam room and ice igloo, while the David Rockwell-blueprinted treatment rooms (all 54 of them) are appropriately stylish and relaxing. A visit here can have you layered in mud, salt or seaweed, or encased in a full body cocoon.